Three New Asperentin Derivatives from the Algicolous Fungus Aspergillus sp. F00785

نویسندگان

  • Qian Tang
  • Kai Guo
  • Xiao-Yang Li
  • Xiu-Ying Zheng
  • Xiang-Jian Kong
  • Zhong-Hui Zheng
  • Qing-Yan Xu
  • Xianming Deng
چکیده

Three new asperentin-type compounds, 6-O-α-d-ribosylasperentin (1) and 6-O-α-d-ribosyl-8-O-methylasperentin (2) and 5-hydroxyl-6-O-methylasperentin (3), along with asperentin (4) and its known analogues (5-9), were isolated from a halotolerant Aspergillus sp. strain F00785, an endotrophic fungus from marine alga. Their structures were determined using extensive NMR and HRESIMS spectroscopic analysis, including the X-ray crystallographic data for the assignment of the absolute configurations of compound 9. Compound 4 exhibited highly potent inhibitory activity against crop pathogens, Colletotrichum gleosporioides Penz. and Colletotrichum gleosporioides (Penz.) Sacc.

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عنوان ژورنال:

دوره 12  شماره 

صفحات  -

تاریخ انتشار 2014